
Hernia Mesh: Uses, Advantages, Type and Cost
Table of Contents
Key Takeaways
- Hernia mesh is a medical-grade implant used to strengthen weak tissue during hernia repair surgery
- Modern meshes include synthetic, biosynthetic, and biologic options with advanced materials
- Lightweight and 3D meshes reduce chronic pain and improve patient comfort compared to older designs
- Mesh cost in India ranges from ₹5,000 to ₹50,000 depending on type and brand
- Not every hernia requires mesh—small hernias in children and teenagers often heal without it
- At Habilite Clinics, Dr. Kapil Agrawal uses the latest mesh technology for optimal patient outcomes
When you're facing hernia surgery, you may have heard your doctor mention something called "mesh." If you're wondering what it is, whether you need it, and how much it costs, you're in the right place.
At Habilite Clinics, our team understands that hernia surgery can feel overwhelming. We're here to explain everything in simple terms. In this guide, Dr. Kapil Agrawal, one of Delhi's most experienced and best hernia surgeons, breaks down the latest information about hernia mesh—what it is, the types available in 2025, their costs, and when you actually need one.
Let's start with the basics.
Understanding Hernia: A Quick Overview
A hernia happens when an organ or tissue pushes through a weak spot in your muscle wall. Think of it like a tire with a bulge—the inner tube pushes through a weak area in the tire.
The most common types of hernia we treat at Habilite Clinics include:
Inguinal hernia (in the groin area)
Umbilical hernia (near the belly button)
Incisional hernia (at the site of a previous surgery)
Femoral hernia (in the upper thigh)
Hiatus hernia (when part of the stomach pushes through the diaphragm)
Hernias don't heal on their own in adults. Surgery is the only permanent solution. That's where hernia mesh comes in.
What is Hernia Mesh?
Hernia mesh is a flat, medical-grade implant that acts like a reinforcement patch. It's placed over or under the weakened area during surgery to strengthen it.
Think of it like patching a hole in your jeans with a strong piece of fabric from the inside. The mesh holds everything in place while your body heals around it.
Most modern hernia meshes are made from biocompatible materials. This means your body won't reject them. They stay in place permanently, becoming part of your body's tissue over time.
Why Do We Use Mesh in Hernia Surgery?
Before mesh technology, surgeons repaired hernias by stitching the torn muscle back together. The problem? High recurrence rates—meaning the hernia came back.
Mesh changed everything. Here's why our team at Habilite Clinics recommends it for most adult hernias:
1. Tension-Free Repair
The mesh covers the defect without pulling the muscle together under tension. This reduces pain after surgery and speeds up recovery.
2. Lower Recurrence Rates
Studies show that mesh repairs have significantly lower recurrence rates compared to suture-only repairs. According to the American College of Surgeons, synthetic mesh reduces hernia recurrence rates to less than 5% in most cases.
3. Stronger, Long-Term Support
The mesh provides a strong scaffold for your body's own tissue to grow into. Over time, it integrates completely, creating a permanent reinforcement.
4. Better for Larger Hernias
The bigger the hernia, the more important mesh becomes. Large defects simply can't be closed with sutures alone—mesh is essential.
Types of Hernia Mesh
Mesh technology has advanced significantly. At Habilite Clinics, we stay updated with the latest options to give you the best results. Here's what's available:
Quick Comparison: Simple vs Composite vs Biologic Mesh
Before we dive into details, here's a simple table comparing the three main categories of hernia mesh:
| Feature | Simple Synthetic Mesh | Composite Mesh | Biologic Mesh |
|---|---|---|---|
| Made Of | Single layer of synthetic material (polypropylene, polyester, or ePTFE) | Two layers: synthetic mesh + anti-adhesion barrier (collagen, hydrogel, ePTFE, or ORC) | Animal-derived tissue (porcine or bovine) that's been processed and sterilized |
| Permanence | Permanent (stays in body forever) | Permanent mesh + temporary barrier (barrier absorbs in 30 days to 3 months) | Gradually absorbed and replaced by your own tissue (6–18 months) |
| Primary Use | When mesh is NOT in direct contact with internal organs (open repairs, preperitoneal placement) | When mesh WILL touch internal organs (laparoscopic ventral, incisional, umbilical hernias) | Contaminated or infected hernias, high-risk patients, complex abdominal wall reconstruction |
| Best For | Inguinal hernias (open), preperitoneal repairs, clean cases, cost-effective option | Laparoscopic ventral, umbilical, incisional hernias—anywhere mesh touches bowel | Infected hernias, contaminated fields, patients with previous mesh complications |
| Adhesion Risk | HIGH if placed against intestines. Safe when placed outside peritoneal cavity. | LOW—anti-adhesion barrier minimizes contact with organs during healing | LOW—natural tissue integration, less inflammatory response |
| Recurrence Rate | LOWEST (less than 5% in most studies) | LOW (5–10%)—similar to simple synthetic mesh | HIGHER (15–40% in some studies at 5 years) |
| Cost in India | ₹5,000–₹25,000 | ₹18,000–₹35,000 | ₹40,000–₹1,50,000 |
| Common Brands | Prolene, Marlex, Bard Soft Mesh, 3D Max | Parietex PCOx, Ventralight ST, Composix L/P, Proceed, Ultrapro | Strattice, Permacol, AlloDerm, XenMatrix, Bio-A |
| Key Advantages | Most affordable • Proven track record • Lowest recurrence • Strong, durable | Safe for organ contact • Low recurrence rates • Versatile placement • Modern standard | • Safe in infected fields • Natural tissue integration • Low infection risk |
| Key Limitations | • Cannot touch organs safely • Limited to certain placements | • More expensive • Some barriers are temporary | • Highest cost • Higher recurrence • Limited evidence vs. synthetic |
At Habilite Clinics, Dr. Kapil Agrawal uses this decision framework: Clean hernia + no organ contact = Simple mesh. Laparoscopic ventral hernia + organ contact = Composite mesh. Infected hernia or high-risk patient = Consider biologic or biosynthetic mesh.
1. Synthetic Mesh (Most Common)
Material: Made from synthetic materials like polypropylene, polyester, or ePTFE (expanded polytetrafluoroethylene)
How it works: These meshes are permanent. Your body forms scar tissue around them, creating a strong bond. They're the gold standard for most hernia repairs.
Subtypes:
Standard polypropylene mesh: Widely used, durable, cost-effective (₹5,000–₹12,000)
Lightweight mesh: Thinner filaments, larger pores, less foreign material. Reduces chronic pain and stiffness. More comfortable than older heavyweight meshes (₹12,000–₹22,000)
3D mesh: Pre-shaped to fit anatomical contours. Used mainly for inguinal hernias in laparoscopic surgery (₹15,000–₹25,000)
Composite/dual-sided mesh: Has two different surfaces—one prevents adhesions to internal organs; the other promotes tissue ingrowth. Ideal for ventral and incisional hernias (₹22,000–₹38,000). See detailed breakdown below.
Self-fixating mesh: Has tiny grips that hold it in place without additional tacks or sutures. Reduces pain from fixation devices (₹20,000–₹35,000)
Best for: Most adult patients with clean, non-infected hernias
Understanding Composite Mesh: The Advanced Option
Composite meshes deserve special attention because they solve a critical problem: what happens when mesh touches your intestines?
When standard polypropylene mesh comes in contact with internal organs, it can cause adhesions (abnormal attachments). This is especially problematic in ventral and incisional hernia repairs where the mesh is placed inside your abdomen.
That's where composite meshes come in. They have two different sides:
Visceral side (facing your organs): A smooth, non-stick barrier coating that prevents adhesions
Parietal side (facing your abdominal wall): Textured polypropylene that promotes strong tissue ingrowth
This dual-sided design allows safe intraperitoneal placement (inside the abdominal cavity) while maintaining the strength and durability of synthetic mesh.
Types of Composite Mesh Available in India
At Habilite Clinics, Dr. Kapil Agrawal uses several types of composite mesh depending on your hernia type and surgical approach. Here's what you need to know:
1. Parietex™ Composite Mesh (Medtronic/Covidien)
Structure: Lightweight polyester mesh + absorbable collagen barrier
How it works: The collagen barrier (made from porcine collagen) covers one side. It prevents adhesions for 7–30 days while your peritoneum (abdominal lining) regenerates. Once healed, the collagen absorbs, leaving behind the permanent polyester mesh bonded to your abdominal wall.
Versions available:
Parietex™ Composite (PCO): Standard version with collagen barrier
Parietex™ Composite Optimized (PCOx): Newer generation with stronger barrier, better visibility, improved textile strength
Parietex™ Composite Ventral Patch: Pre-shaped for small ventral hernias with deployment handles
Best for: Laparoscopic ventral hernia repair, umbilical hernias, incisional hernias, hiatus hernias, parastomal hernias
Cost in India: ₹19,500–₹25,000 (depending on size)
Advantages: Macroporous (large pores), lightweight, hydrophilic (absorbs fluid for better conformability), excellent tissue integration
2. Ventralight™ ST Mesh (BD/Bard)
Structure: Medium-weight uncoated polypropylene + absorbable hydrogel barrier (Sepra® Technology)
How it works: The hydrogel barrier provides visceral protection during the critical first 30 days of healing, then completely resorbs. The open-pore polypropylene allows strong tissue ingrowth within 2 weeks.
Key feature: Studies show 42% less mesh contraction at 4 weeks compared to other composite meshes. Less contraction means lower recurrence risk.
Best for: Laparoscopic ventral hernia repair, incisional hernias, umbilical hernias
Cost in India: ₹24,000–₹32,000
Advantages: Low-profile design, available in multiple shapes (circle, oval, ellipse, rectangle), can be used with Echo PS™ positioning system for easier deployment
3. Composix™ L/P Mesh (BD/Bard)
Structure: Large-pore polypropylene mesh + smooth ePTFE (expanded polytetrafluoroethylene) barrier
How it works: The ePTFE layer is permanent and provides a smooth, non-adhesive surface against your organs. Unlike collagen or hydrogel barriers that absorb, this layer stays permanently but doesn't promote adhesions.
Best for: Ventral hernias, chest wall defects, situations where long-term anti-adhesion barrier is needed
Cost in India: ₹26,000–₹35,000
Advantages: Permanent anti-adhesion barrier, excellent for re-operations, available with Echo PS™ positioning system
4. Proceed™ Mesh (Ethicon)
Structure: Lightweight polypropylene + oxidized regenerated cellulose (ORC) barrier layer
How it works: The ORC layer creates a protective gel-like surface when it comes in contact with body fluids. This minimizes adhesions during early healing. The ORC layer is absorbed within weeks, leaving the permanent polypropylene mesh.
Best for: Ventral hernia repair, both laparoscopic and open techniques
Cost in India: ₹22,000–₹30,000
Note: Proceed mesh had some recalls in the past due to delamination (layers separating). Current versions have addressed these issues, but we carefully evaluate each patient before recommending this mesh.
5. Ultrapro™ Mesh (Ethicon)
Structure: Partially absorbable composite—lightweight polypropylene + absorbable Monocryl (poliglecaprone)
How it works: About 50% of the mesh is absorbable material. This provides initial support while your tissue heals, then absorbs over 3–4 months. The remaining polypropylene provides permanent reinforcement with less foreign material.
Best for: Inguinal hernias (especially with Ultrapro Hernia System), ventral hernias, patients concerned about foreign material
Cost in India: ₹18,000–₹28,000
Advantages: Reduced foreign body sensation, excellent for active patients, lower chronic pain rates compared to heavyweight mesh
Which Composite Mesh Should You Choose?
At Habilite Clinics, Dr. Kapil Agrawal selects composite mesh based on your specific situation:
For laparoscopic ventral hernia repair: Parietex™ Composite PCOx or Ventralight™ ST are excellent first choices. Both have absorbable barriers and excellent outcomes.
For incisional hernias (previous surgery site): Ventralight™ ST or Composix™ L/P. The permanent ePTFE barrier in Composix™ is especially useful if there's scar tissue from your previous surgery.
For umbilical hernias: Parietex™ Composite Ventral Patch (pre-shaped) or Ventralight™ ST in appropriate sizes.
For hiatus hernias: Parietex™ Composite specially configured for hiatus hernia repair.
For patients concerned about foreign material: Ultrapro™ (partially absorbable) offers a good balance of support with less permanent material.
Budget-conscious without compromising quality: Proceed™ or Ultrapro™ offer good value at ₹18,000–₹30,000 range.
For best outcomes: Parietex™ PCOx or Ventralight™ ST are our top recommendations for most laparoscopic ventral and incisional hernia repairs.
When NOT to Use Composite Mesh
Composite mesh is not always necessary. Here's when we use standard polypropylene instead:
Open inguinal hernia repair: Standard lightweight polypropylene works excellently because it's placed outside the abdominal cavity (no organ contact)
Preperitoneal placement: When mesh is placed between muscle layers (not touching organs), composite mesh isn't needed
Budget limitations: Standard mesh costs ₹5,000–₹15,000 vs. ₹22,000–₹35,000 for composite. If you can't afford composite mesh, we can often achieve excellent results with careful placement of standard mesh in many cases
Our team at Habilite Clinics discusses all options with you during consultation, considering both clinical needs and budget.
2. Biosynthetic Mesh (Latest Technology)
Material: Made from poly-4-hydroxybutyrate (P4HB), a long-lasting resorbable material
How it works: This mesh supports your tissue while it heals, then gradually dissolves over 12–18 months. Your body replaces it with natural collagen tissue. It's like a temporary scaffold that disappears once the building is complete.
Latest research: According to 2025 studies published in the Journal of the American College of Surgeons and Journal of Abdominal Wall Surgery, biosynthetic meshes like Phasix™ show similar 1-year outcomes to permanent synthetic mesh. They're especially useful in contaminated or higher-risk cases.
Cost: ₹35,000–₹50,000
Best for: Patients at higher risk of infection, complex hernias, or those who prefer absorbable materials
3. Biologic Mesh
Material: Made from animal tissue (usually porcine or bovine) that has been specially processed
How it works: Your body gradually replaces the biologic mesh with your own tissue. It's absorbed over time, similar to biosynthetic mesh.
Important note: While biologic mesh has advantages in contaminated fields, recent research shows that in clean cases, synthetic mesh often performs better with lower recurrence rates. At Habilite Clinics, Dr. Kapil Agrawal reserves biologic mesh for specific situations—like infected hernias or complex abdominal wall reconstructions.
Cost: ₹40,000–₹150,000 (most expensive option)
Best for: Contaminated or infected hernias, patients with previous mesh complications.
Hernia Mesh Cost in India
One of the most common questions our patients ask is, "How much will the mesh cost?" The answer depends on the type and brand. Here's a detailed breakdown:
| Mesh Type / Brand | Cost Range (₹) | Best For |
|---|---|---|
| Standard Polypropylene | ₹4,000–₹12,000 | Open inguinal hernias, standard repairs |
| Lightweight Mesh | ₹5,000–₹22,000 | Active patients, reduced pain risk |
| 3D Mesh | ₹10,000–₹25,000 | Laparoscopic inguinal hernia |
| Ultrapro™ (Ethicon) | ₹18,000–₹28,000 | Inguinal & ventral hernias, partially absorbable |
| Parietex™ PCO/PCOx (Medtronic) | ₹19,500–₹25,000 | Laparoscopic ventral, umbilical, incisional hernias |
| Proceed™ (Ethicon) | ₹22,000–₹30,000 | Ventral hernia, laparoscopic & open |
| Ventralight™ ST (BD/Bard) | ₹24,000–₹32,000 | Laparoscopic ventral, umbilical, incisional |
| Composix™ L/P (BD/Bard) | ₹26,000–₹35,000 | Ventral hernias, chest wall, re-operations |
| Biosynthetic Mesh (Phasix™) | ₹35,000–₹50,000 | Complex or higher-risk cases |
| Biologic Mesh | ₹40,000–₹1,50,000 | Infected/contaminated hernias |
Note: These are mesh costs only. The total hernia surgery cost includes surgeon fees, hospital charges, anesthesia, and pre-operative tests. At Habilite Clinics, we provide transparent pricing and discuss all options during your consultation.
Most health insurance plans in India cover hernia surgery and mesh costs. Our team at Habilite Clinics assists with insurance paperwork to make the process smoother for you.
Is Mesh Required in Every Hernia Surgery?
Here's an important fact: not every hernia needs mesh.
Dr. Kapil Agrawal, with over 23 years of experience and 7,000+ hernia surgeries, explains that mesh decisions are highly individualized. They depend on:
Size of the hernia: Small defects may heal well with sutures alone
Patient age: Young children and teenagers have better tissue quality and can often heal without mesh
Type of hernia: Certain hernias like small umbilical hernias in newborns close on their own
Overall health: Some medical conditions may influence the decision
When mesh is typically NOT needed:
Small inguinal hernias in children or teenagers
Very small umbilical hernias in healthy young adults
Certain femoral hernias in specific cases
When mesh IS recommended:
Large hernias (greater than 3 cm)
Recurrent hernias (hernias that have come back after previous surgery)
Most adult inguinal and femoral hernias
Incisional hernias (after abdominal surgery)
Ventral and umbilical hernias in adults
At Habilite Clinics, our approach is evidence-based and patient-centered. We discuss your specific situation and recommend mesh only when it truly improves your outcome.
How Do We Choose the Right Mesh for You?
At Habilite Clinics, Dr. Kapil Agrawal considers multiple factors before selecting a mesh:
1. Hernia Location and Size
For inguinal hernias repaired laparoscopically, we typically use 3D mesh or lightweight polypropylene. For ventral hernias, composite mesh works best to prevent adhesions.
2. Surgical Technique
Different meshes suit different techniques:
Laparoscopic surgery: 3D anatomical mesh or dual-sided composite mesh
Robotic surgery: Self-fixating or lightweight mesh (at Habilite Clinics, we offer both robotic and laparoscopic repairs)
Open surgery: Standard polypropylene or lightweight mesh
3. Patient Activity Level
Athletes or physically active patients benefit from lightweight mesh. It flexes better with movement and reduces the risk of chronic pain.
4. Medical History
If you have diabetes, obesity, or previous mesh complications, we may consider biosynthetic or biologic options. If there's an infection risk, biosynthetic mesh is often the safer choice.
5. Budget and Insurance Coverage
Our team at Habilite Clinics is transparent about costs. We work within your budget and insurance coverage to find the best mesh option for your situation.
Latest Advances in Hernia Mesh Technology
Hernia mesh technology continues to evolve. Here's what's new in 2025:
1. Lightweight Designs Reduce Chronic Pain
Modern lightweight meshes use thinner filaments and larger pore sizes. This allows better tissue integration and reduces the "foreign body feeling" that older heavyweight meshes sometimes caused.
2. Biosynthetic Meshes Show Promising Results
Recent research from the American College of Surgeons (January 2025) shows that biosynthetic meshes like Phasix™ perform as well as permanent synthetic mesh at one year, with the advantage of being fully absorbed. This is especially valuable in contaminated cases where infection risk is high.
3. Self-Fixating Meshes Eliminate Tacks
These meshes have tiny microgrips that hold them in place without metal tacks or sutures. Result? Less post-operative pain and faster recovery.
4. Smart Coatings Prevent Adhesions
Composite meshes now come with anti-adhesion coatings on one side. This prevents the mesh from sticking to your intestines—a key advantage for ventral and incisional hernia repairs.
5. 3D Anatomical Mesh for Better Fit
Pre-shaped 3D meshes conform to your body's natural contours, especially in the groin area. They're easier to place and provide a more comfortable fit.
Is Hernia Mesh Safe?
You may have heard concerns about mesh safety in the news. Let's address this with facts.
The truth: Hernia mesh is safe for the vast majority of patients.
According to research published by the American College of Surgeons and recent 2025 studies, synthetic mesh reduces hernia recurrence significantly compared to suture-only repairs. Complications are rare when the surgery is performed by experienced surgeons using the right techniques.
Potential complications (rare):
Infection (less than 1–2% in clean cases)
Chronic pain (reduced significantly with lightweight mesh)
Mesh migration (very rare with proper fixation)
Recurrence (less than 5% with mesh vs. 15–30% without mesh)
At Habilite Clinics, Dr. Kapil Agrawal follows international best practices. We use high-quality, FDA-approved meshes and minimally invasive techniques to minimize risks and optimize your recovery.
Hernia Surgery at Habilite Clinics: Why Choose Us?
At Habilite Clinics, we combine experience, advanced technology, and patient-centered care to deliver the best hernia surgery outcomes in Delhi.
Our Expertise
23+ years of surgical experience with Dr. Kapil Agrawal
7,000+ successful hernia surgeries performed
Laparoscopic and robotic surgery expertise (we offer both options based on your hernia type)
State-of-the-art infrastructure at Apollo Hospitals and our own Habilite Clinics locations
Advanced Techniques We Use
Laparoscopic hernia repair: Minimally invasive, faster recovery, less pain
Robotic hernia repair: Greater precision, especially for complex or recurrent hernias
Open hernia repair: When appropriate for larger or complicated hernias
Latest Mesh Technology
We stay updated with the latest mesh options—from lightweight polypropylene to biosynthetic meshes—and select the best one for your specific case.
Transparent Pricing
We discuss all costs upfront, including mesh options. Our team helps with insurance claims and offers cashless facilities at Apollo Hospitals.
Personalized Care
From your first consultation to post-surgery follow-ups, Dr. Kapil Agrawal and our team are with you every step of the way. We explain everything clearly, answer all your questions, and ensure you feel confident about your treatment.
Conclusion
Hernia mesh has revolutionized hernia surgery. With advancements in materials and techniques, mesh repairs are safer, more effective, and more comfortable than ever before.
At Habilite Clinics, we're committed to using the latest mesh technology to give you the best outcome. Whether you need a standard polypropylene mesh or an advanced biosynthetic option, Dr. Kapil Agrawal and our team will guide you through every step.
Remember: the right mesh, combined with expert surgical technique, makes all the difference. Don't let a hernia hold you back from living your life fully.
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Frequently Asked Questions
Most synthetic meshes are permanent and last a lifetime. Biosynthetic meshes dissolve over 12–18 months but leave behind strong collagen tissue. Biologic meshes are absorbed, and your body replaces them with natural tissue.
Most patients don't feel the mesh after full recovery. Modern lightweight meshes are designed to integrate smoothly with your tissue. You might feel some stiffness initially, but this usually resolves within a few weeks.
In rare cases where complications occur, mesh can be removed. However, this is very uncommon. At Habilite Clinics, we use techniques that minimize the need for future interventions.
For laparoscopic inguinal hernia repair, 3D mesh or lightweight polypropylene mesh works best. Dr. Kapil Agrawal will recommend the ideal option based on your hernia size and surgical approach
Yes, most health insurance plans in India cover hernia surgery, including mesh costs. Our team at Habilite Clinics assists with all paperwork and offers cashless facilities at empanelled hospitals.
Yes, most health insurance plans in India cover hernia surgery, including mesh costs. Our team at Habilite Clinics assists with all paperwork and offers cashless facilities at empanelled hospitals.
With laparoscopic or robotic surgery, most patients return to desk jobs within 1–2 weeks. For physically demanding jobs, we recommend 4–6 weeks. Recovery is faster with minimally invasive techniques.
Yes. Light walking is encouraged immediately after surgery. You can gradually resume normal activities after 2–3 weeks. Heavy lifting and strenuous exercise should wait 6–8 weeks. Our team provides a detailed recovery plan tailored to your lifestyle.
3D mesh is pre-shaped to fit the contours of your groin area, making it ideal for laparoscopic inguinal hernia repairs. Regular (flat) mesh requires more manual shaping during surgery. 3D mesh offers better anatomical fit and easier placement.
You can resume a normal diet soon after surgery. We recommend eating high-fiber foods to prevent constipation, which can strain the repair site. Avoid heavy, spicy meals immediately post-surgery
If you have a visible bulge in your groin or abdomen, pain, discomfort, or difficulty with daily activities, it's time to see a surgeon. Hernias don't heal on their own in adults—surgery is the only permanent solution. Book a consultation with Dr. Kapil Agrawal at Habilite Clinics for an accurate diagnosis and personalized treatment plan.
Dr. Kapil Agrawal
Senior Consultant at Apollo Group of Hospitals
About the Doctor

Dr. Kapil Agrawal
Senior Consultant - Laparoscopic & Robotic Surgeon
Dr. Kapil Agrawal is a leading and one of the best Robotic and Laparoscopic Surgeon in Delhi, India. He has an overall experience of 23 years and has been working as a Senior Consultant Surgeon at Apollo Group of Hospitals, New Delhi, India. He is performing advanced laparoscopic and robotic surgeries for various conditions, which include Gallbladder stones, Hernia, Appendicitis, Rectal prolapse, and pseudo-pancreatic cyst.
Qualifications
- •MBBS - Institute of Medical Sciences, BHU, Varanasi
- •MS (Surgery) - Institute of Medical Sciences, BHU, Varanasi
- •MRCS (London, U.K) - Royal College of Surgeons, London